Hepatitis C: Home Page

<body><!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> <html xmlns="http://www.w3.org/1999/xhtml"> <head><link rel="stylesheet" media="print" href="https://www.ark.org/siteheader/print.css" type="text/css" /> <style type="text/css"> @media print { #banner, #topnav, #logo, #empty, #arlogo, .noprint { display: none; } } @media screen { #banner { margin-top:0px; margin-left:0px; margin-right:0px; } } </style> <style type="text/css"> body {font-size:100%; margin:0px; padding:0px;} #banner{ background-color: #FFFFFF; width: 100%; height: 30px; border-bottom: 1px solid #747A7C; padding:0px; margin:0px;} #topnav{ margin-top:-18px; font-family: Arial; text-align:right; color: #747A7C; background-color: transparent; font-size: 11px; position:relative; text-decoration:none; font-weight: bold; padding-right:10px;} #topnav a:link { text-align:right; color: #747A7C; background-color: transparent; font-size: 11px; text-decoration:none;} #topnav a:visited {text-align:right; 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detectable in persons with acute, chronic, and resolved infection.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">AST</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Aspartate aminotransferase.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Chronic (persistent) HCV Infection</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Persistent infection with HCV; characterized by detection of HCV RNA <u>></u> 6 months after newly acquired infection.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0" nowrap><font face="Arial, Helvetica" size="2">Chronic hepatitis C</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Liver inflammation in patients with chronic HCV infection; characterized by abnormal levels of liver enzymes.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">CSTE</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Council of State and Territorial Epidemiologists.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">DNA</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Deoxyribonucleic acid.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">EIA</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Enzyme immunoassay.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">FDA</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">U.S. Food and Drug Administration.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">HBV</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Hepatitis B virus.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">HCC</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Hepatocellular carcinoma.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">HCV</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Hepatitis C virus.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">HCV-positive</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Positive for anti-HCV as verified by supplemental testing or positive for HCV RNA.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">HCV RNA</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Hepatitis C virus ribonucleic acid.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">HIV</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Human immunodeficiency virus.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">IG</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Immune globulin.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">IM</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Intramuscular.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">IV</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Intravenous</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">MSM</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Men who have sex with men.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">NHANES III</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Third National Health and Nutrition Examination Survey.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">NIH</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">National Institutes of Health.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Positive predictive value</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Probability that a positive screening test is truly positive; dependent on prevalence of disease in a population.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Qualitative RT-PCR for HCV RNA</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Test to detect HCV RNA by amplification of viral genetic sequences.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Qualitative assays for HCV RNA</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Test to detect HCV RNA concentration (viral load) by amplification of viral genetic sequences of by signal amplification.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Resolved HCV infection</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Recovery following hepatitis C virus infection; characterized by sustained disappearance of serum HCV RNA and normalization of liver enzymes.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">RIBA</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Recombinant immunoblot assay.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">RNA</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Ribonucleic acid.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">RT-PCR</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Reverse transcriptase polymerase chain reaction.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">STD</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Sexually transmitted disease.</font></td> </tr> <tr> <td valign="top" bgcolor="#FFFFFF"> </td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Supplemental anti-HCV  test</font></td> <td valign="top" bgcolor="#DBDFF0"><font face="Arial, Helvetica" size="2">Additional test (i.e., RIBA) used to verify a positive anti-HCV result obtained by EIA.</font></td> </tr> </table> </div></td> </tr> </table> </div> </body>